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Preface 

In writing this website I believe the initial interest of readers will be in the historical anomalies, which can be recorded in most clinical conditions whether these are of a “human” or medical “nature”.
The other themes are the way investigations occurred, the thoughts behind differential diagnosis and the drawing together of references. The way in which acromegaly is portrayed in medical literature has changed but less than one might expect.

Terminology

Akromakrie akro = end, megas = large

“ La maladie de Marie” proposed name after Pierre Marie, proposed by Verstraten and some of Pierre marie’s students.

Pachyakrie - Von Recklinghausen proposed since the increase in skin thickness is invariable.

Photographic origin of research

A considerable amount of this research has derived from my interest in the relationship between acromegaly and images, especially photographs. All the small images link to larger ones and I also have still larger versions on file or can put together a collection on CD if some could be useful for teaching purposes. (Please contact me by e-mail This e-mail address is being protected from spambots. You need JavaScript enabled to view it )

Original papers from journals or books were photographed on Kodak Recordak using a Leitz Reprovit (1981-2) and subsequent on Ilford Pan F. Negatives were copied using Kodak Fine Grain Positive for early lectures and printed using Ilford Multigrade paper.

The thought of printing out some 700 images meant the project was very much put on hold and has now been rejuvenated with the possibility of scanning quantities of negatives with ease.

Scanner Nikon Super Coolscan 4000 with slide adapter and roll-film adapter.

Negatives scanned at 300ppi enlarged to A3, jpg quality 100%. (ppi pixels per inch)

Files used on website are:

  • In-line images 72ppi, jpg quality 80%, max width 320 pixels, maximum height 200 pixels (reversed for vertical images)
  • Linked images 72ppi, jpg quality, max width 640 pixels, maximum height 400 pixels (reversed for vertical images).

Website specification

The original site was designed using Macromedia Studio MX 2004 on Macintosh OSX platform using Dreamweaver templates, stylesheets and is compliant to W3C XHTML and CSS2 standards it has since been transferred along with the rest of my website onto a Content Management System joomla 1.0.12 and now joomla 1.5.4. Some parts may require Flash Player 9. Accessibility is to AAA standard throughout.

The family of acromegalics

"There are very few diseases all cases of which appear to present such a strong family likeness." (Hutchinson W 1898)

See PitPat site for patient's story 

Illustration of the Bradford lady from the paper by Appleyard in 1892. Shows kyphosis, sternal protrusion and facial changes due to acromegaly.

. . . . of a Bradford lady. For the last seen or eight years she had not cared to go out at all because "people looked at her so" (Appleyard 1892)

Papers, publications and lectures

http://www.spyrock.com/nadafarm/html/punchlinks.htm

Photographs from my research on acromegaly an gigantism have been used in the following publications:

Anatomy and Physiology 4th Edition Brooks/Cole Thomson Learning 2000.

An Illustrated History of Acromegaly: Diagnosis and Treatment (Slide resource kit) Ipsen Ltd, Produced by Medical Action Communications Ltd, edited by Professor Stafford Lightman, 1998.

Lectures

History of Medical Photography in the Guise of Acromegaly
Institute of Medical and Biological Illustration Conference, Warwick University, September 1983.

Illustrated History of Acromegaly and Gigantism
Bristol Medical History Society, Frenchay Postgraduate Medical Centre, November 1983
Endocrinology Club, St Bartholomew's Hospital, London, February 1984
Kidderminster Medical Society, Kidderminster Postgraduate Medical Centre, April 1984.

Acknowledgements

This website would not have been possible without the help of many people including the many librarians, museums and archivists who have put up with my many and varied, and some would say strange, requests. I would especially like to thank those who have freely given me copies of papers and photographs.

The following list is not exhaustive but I will be adding to it as I finish writing up.

Dundee Ninewells Medical School Library
Somerset County Museum
Jonathan Musgrave, University of Bristol
Kunsthistorisches Museum, Burgring, Wien.
Worcester Public Library
Hunterian Museum, The Royal College of Surgeons of England.
University of Derby, Library and Learning Resource Centre
Scarborough Borough Council, Department of Tourism and Amenities

Nancy W Zinn, Head of Special Collections, The Library, University of California, San Francisco for photocopy of paper by Ellinwood.

 

 

 

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